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Clinical observation of Tongluo Zhitong external application combined with electromagnetic spectrum physiotherapy in the treatment of osteoarthritis of knee

Phase 1
Recruiting
Conditions
Osteoarthritis of the knee
Registration Number
ITMCTR2100004661
Lead Sponsor
Tianjin Jizhou Traditional Chinese Medicine Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1.Aged 40-75 years, male or female;
2.According to the diagnostic criteria of knee osteoarthritis.
(1)Repeated knee pain in recent 1 month;
(2)The time of morning stiffness of knee joint was less than or equal to 30 min;
(3)There are bone frications in the knee joint during physical activity;
(4)X-ray film (standing or weight-bearing position) showed narrowing of knee joint space, subchondral osteosclerosis and/or cystic degeneration, osteophyte formation at the edge of the joint;
(5)MRI showed cartilage injury, osteophyte formation, subchondral bone marrow edema and (or) cystic degeneration, meniscal degenerative tear, partial or full-thickness cartilage loss;
(Note: koa can be diagnosed if it meets the diagnostic criteria of 1+2+3or1+4or1+5)
3.Patients who have not received local or oral medication or surgery for knee joint in recent two weeks;
4.The patients who agree and sign the informed consent, can adhere to the treatment on schedule and cooperate with the doctor.

Exclusion Criteria

1.All patients with fever or skin infection at the treatment site;
2.Severe heart, liver and kidney insufficiency or systemic failure;
3.Patients with pain around knee joint and limited movement caused by bone tuberculosis, bone tumor and fracture;
4.Treat the patients with acute injury of knee joint.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
WOMAC rating scale;NRS;Lysholm;HSS;
Secondary Outcome Measures
NameTimeMethod
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