New Ultrasound Parameters for Predicting Birthweight

Completed

• Conditions: Fetal Development

• Registration Number: NCT02196363
• Lead Sponsor: Manchester University NHS Foundation Trust

Brief Summary

Babies that are either very small or very big have increased perinatal morbidity and mortality. Predicting which babies will fall into these groups is traditionally done with risk assessment and third trimester manual palpation, however neither of these techniques are sensitive and a considerable number of affected pregnancies are missed. This results in stillbirth for small babies or birth trauma for larger ones. Serial scanning in the third trimester can improve detection rates but this is expensive and cannot currently be provided to all NHS patients.

A more sensitive test that can be performed earlier in pregnancy would allow identification of at risk pregnancies allowing for increased monitoring. New three dimensional ultrasound techniques that measure volume and volumetric flow have become available that may allow this to happen. This study proposes to trial newer ultrasound techniques on a cohort of pregnant women. The findings from these scans will then be correlated with actual birth weights at the end of pregnancy to determine the ability of these parameters to act as screening tools for babies at the extremes of size.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07
• Study First Submitted: 2014-07-16
• Study First Submitted QC: 2014-07-21
• Study First Posted: 2014-07-22
• Primary Completion: 2015-02
• Study Completion: 2015-07
• Status Verified: 2018-11
• Last Update Submitted: 2018-11-30
• Last Update Posted: 2018-12-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 253

Inclusion Criteria

• Pregnant women the beginning of pregnancy to term

Exclusion Criteria

• Pregnancies in women previously affected by unclassfied fetal abnormality
• Multiple pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Kidney volume, thigh volume, placental volume, brain volume, final birthweight	up to 34-36 weeks pregnancy gestation

Trial Locations

Locations (1)

Central Manchester University Hospitals NHS Foundation Trust; 🇬🇧 Manchester, United Kingdom