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Clinical Trials/NCT02196363
NCT02196363
Completed
Not Applicable

New Ultrasound Parameters for Predicting Birthweight

Manchester University NHS Foundation Trust1 site in 1 country253 target enrollmentJuly 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Fetal Development
Sponsor
Manchester University NHS Foundation Trust
Enrollment
253
Locations
1
Primary Endpoint
Kidney volume, thigh volume, placental volume, brain volume, final birthweight
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Babies that are either very small or very big have increased perinatal morbidity and mortality. Predicting which babies will fall into these groups is traditionally done with risk assessment and third trimester manual palpation, however neither of these techniques are sensitive and a considerable number of affected pregnancies are missed. This results in stillbirth for small babies or birth trauma for larger ones. Serial scanning in the third trimester can improve detection rates but this is expensive and cannot currently be provided to all NHS patients.

A more sensitive test that can be performed earlier in pregnancy would allow identification of at risk pregnancies allowing for increased monitoring. New three dimensional ultrasound techniques that measure volume and volumetric flow have become available that may allow this to happen. This study proposes to trial newer ultrasound techniques on a cohort of pregnant women. The findings from these scans will then be correlated with actual birth weights at the end of pregnancy to determine the ability of these parameters to act as screening tools for babies at the extremes of size.

Registry
clinicaltrials.gov
Start Date
July 2010
End Date
July 2015
Last Updated
7 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Pregnant women the beginning of pregnancy to term

Exclusion Criteria

  • Pregnancies in women previously affected by unclassfied fetal abnormality
  • Multiple pregnancy

Outcomes

Primary Outcomes

Kidney volume, thigh volume, placental volume, brain volume, final birthweight

Time Frame: up to 34-36 weeks pregnancy gestation

Study Sites (1)

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