E-Vent: Electrical muscle stimulation in mechanical Ventilatio

Not Applicable

Completed

• Conditions: Critically ill patients receiving prolonged periods of mechanical ventilation; Respiratory

• Registration Number: ISRCTN35179428
• Lead Sponsor: niversity Hospitals Bristol NHS Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-01-31
• Study Completion: 2013-09-30
• Last Update Posted: 5 May 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

1. The target population is critically ill patients expected to receive prolonged mechanical ventilation (MV)
2. 18 years or older, male and female
3. Expected to receive MV for > 72 hour

Exclusion Criteria

1. Body mass index < 15 kg/m² or > 35kg/m²
2. Pre-existing neuromuscular conditions affecting peripheral nervous system
3. Pacemaker or implanted cardiac defibrillator
4. Skin lesions making electrode placement impossible
5. Current upper and/ or lower limb fractures
6. Current pregnancy
7. Unable to walk or perform transfers prior to acute illness
8. Chronic renal disease
9. Chronic liver failure (Child Pugh score >3)
10. Irreversible disease with < 6 months prognosis
11. Long term oral steroid use >10mg
12. Uncontrolled / difficult to control epilepsy

Study & Design

• Study Type: Interventional
• Study Design: Not specified