Feasibility of Online MR-guided Radiotherapy on a 1.5T MR-Linac
- Conditions
- Rectal CancerHead and Neck CancerLiver CancerBreast CancerEsophageal CancerProstate CancerOligometastasis
- Registration Number
- NCT04172753
- Lead Sponsor
- University Hospital Tuebingen
- Brief Summary
This study investigates the feasibility of imaging and treatment on a novel 1.5 T MR-Linac radiotherapy hybrid device.
- Detailed Description
Novel hybrid devices combine magnetic resonance imaging (MRI) and a linear accelerator in a single device. The superior soft tissue contrast compared with cone-beam computed tomography based treatment and the possibility for daily plan adaptation promise a higher precision of treatment, better target volume coverage and normal tissue sparing. In a first step the present study will test the feasibility of imaging and treatment on the 1.5 T MR-Linac.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 472
- existing indication for radiation therapy
- minimum age 18 years, no upper age limit
- capacity for consent
- Informed consent
- contraindication for MRI (claustrophobia, metallic implants not applicable for MRI
- pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Feasibility of online MR guided Radiotherapy During every single patients treatment (i.e. between one to seven weeks after the first application of radiotherapy) Treatment of a patient is considered feasible when 85% of treatments were completed as planned in this patient
- Secondary Outcome Measures
Name Time Method Time analysis During every single patients treatment (i.e. between one to seven weeks after the first application of radiotherapy) Time required for online MR guided radiotherapy
Trial Locations
- Locations (1)
University Hospital Tübingen, Department of Radiation Oncology
🇩🇪Tübingen, Baden-Württemberg, Germany
University Hospital Tübingen, Department of Radiation Oncology🇩🇪Tübingen, Baden-Württemberg, Germany