Feasibility of Imaging and Radiotherapy on a Novel 1.5 T Hybrid Magnetic Resonance Imaging - Linear Accelerator System (MR-Linac)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 472
- 试验地点
- 2
- 主要终点
- Feasibility of online MR guided Radiotherapy
研究概览
简要总结
This study investigates the feasibility of imaging and treatment on a novel 1.5 T MR-Linac radiotherapy hybrid device.
详细描述
Novel hybrid devices combine magnetic resonance imaging (MRI) and a linear accelerator in a single device. The superior soft tissue contrast compared with cone-beam computed tomography based treatment and the possibility for daily plan adaptation promise a higher precision of treatment, better target volume coverage and normal tissue sparing. In a first step the present study will test the feasibility of imaging and treatment on the 1.5 T MR-Linac.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •existing indication for radiation therapy
- •minimum age 18 years, no upper age limit
- •capacity for consent
- •Informed consent
排除标准
- •contraindication for MRI (claustrophobia, metallic implants not applicable for MRI
- •pregnancy
结局指标
主要结局
Feasibility of online MR guided Radiotherapy
时间窗: During every single patients treatment (i.e. between one to seven weeks after the first application of radiotherapy)
Treatment of a patient is considered feasible when 85% of treatments were completed as planned in this patient
次要结局
- Time analysis(During every single patients treatment (i.e. between one to seven weeks after the first application of radiotherapy))
研究者
Dr. Cihan Gani
Lead of gastrointestinal radiation oncology
University Hospital Tuebingen