Effect of Different Form of Upper Limb Muscles Training on Dyspnea in COPD

Not Applicable

Completed

• Conditions: COPD
• Interventions: Other: Strength training; Other: Endurance training

• Registration Number: NCT03611036
• Lead Sponsor: University Hospital, Brest

Brief Summary

Evaluate the effect of upper limbs strength training versus the effect of upper limbs endurance training, on dyspnea, in patients with COPD during a pulmonary rehabilitation program.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-07-16
• Study First Submitted QC: 2018-07-26
• Study First Posted: 2018-08-02
• Study Start: 2018-11-21
• Primary Completion: 2023-02-06
• Study Completion: 2023-02-06
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-22
• Last Update Posted: 2025-01-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 280

Inclusion Criteria

• Patient with stage 2 to 4 (A to D) COPD admitted to a pulmonary rehabilitation program (4 weeks)
• Patient aged 18 or over
• Patient able to consent and having signed a consent form

Exclusion Criteria

• Patient with pain, osteoarthritis or shoulder surgery
• Patient with a history of Pneumonectomy, lobectomy less than 6 months old
• Refusal of participation
• Patient with an inability to complete a pulmonary rehabilitation program in totality
• Pregnant or breast-feeding women
• Patient under tutorship or curatorship

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Strength	Strength training	Patients will follow the pulmonary rehabilitation program associated with upper limbs strength training for a duration of 4 weeks
Endurance	Endurance training	Patients will follow the pulmonary rehabilitation program associated with upper limbs endurance training for a duration of 4 weeks

Primary Outcome Measures

Name	Time	Method
Compare the effect of upper limbs strength training versus the effect of upper limb endurance training on dyspnea in patients with COPD during a pulmonary rehabilitation program.	Change from inclusion at 4 week	Measurement of dyspnea using the London Chest Daily Activity Living (LCADL) questionnaire.; This 15-item, self-administered questionnaire allows an evaluation of dyspnea in patients with COPD during daily activities divided into four components: self-care, domestic, physical, and leisure. Patients could score from 0: "I would not do anyway" to 5: "I need someone else to do this". LCADL score is calculated by aggregating the points assigned to each question, with a higher score representing maximal disability.

Secondary Outcome Measures

Name	Time	Method
Compare the evolution of upper limb strength between the 2 groups.	At inclusion and week 4	Measurement of the strength of deltoids, biceps and brachial triceps, with hand held dynamometer
Compare dyspnea in daily life between the 2 groups	At inclusion and week 4	Measurement of dyspnea using Dyspnea-12 questionnaire. This 12-item self-administered questionnaire measures dyspnea severity in both its physical and affective components, independently from activity limitation. Patients score ranges from "none" (corresponding to score 0) to "severe" (score 3). Dyspnea-12 score is calculated by aggregating the points assigned to each question; the higher the score, the greater the severity.
Measuring upper limb endurance	At inclusion and week 4	with the 6-minute Peg Board and Ring Test (6PBRT)
Compare upper limbs muscle fatigue at the end of a functional test using the upper limbs	At inclusion and week 4	Measurement of upper limbs muscle fatigue with Borg scale at the end of 6PBRT. The measure is a rating on a scale from 0 to 10 attached to different words of appreciation: "very light, difficult, painful ..." effort.
Compare dyspnea at the end of a functional test using the upper limbs	At inclusion and week 4	Measurement of dyspnea with Borg scale at the end of 6PBRT. The measure is a rating on a scale from 0 to 10 attached to different words of appreciation: "very light, difficult, painful ..." effort.

Trial Locations

Locations (2)

CHRU de Brest; 🇫🇷 Brest, France

CH Pays de Morlaix; 🇫🇷 Morlaix, France