High Neutrophil-to-Lymphocyte Ratio and Patients With Hemodialysis

Not yet recruiting

• Conditions: Hemodialysis Patient

• Registration Number: NCT07070557
• Lead Sponsor: Sohag University

Brief Summary

To explore the role of neutrophil-to-lymphocyte ratio ( NLR ) and platelet-to-lymphocyte ratio ( PLR ) in predicting mortality in hemodialysis (HD) patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-07
• Study First Submitted: 2025-07-06
• Study Start: 2025-07-15
• Study First Submitted QC: 2025-07-16
• Last Update Submitted: 2025-07-16
• Study First Posted: 2025-07-17
• Last Update Posted: 2025-07-17
• Primary Completion: 2026-02-15
• Study Completion: 2026-05-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• All cases with age ≥ 18 years from both sexes female and male, having end-stage renal disease (ESRD), who have been on hemodialysis for at least three months and divided to 4 groups according to the median of NLR and PLR

Exclusion Criteria

• • Patients aged < 18 years old.

  • Patient with autoimmune disease.
  • Patient with liver cirrhosis.
  • Patients with immunodeficiency.
  • Patients with malignancy.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality	6 months	The primary outcome measures in the study "High Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio Are Associated with Poor Survival in Patients with Hemodialysis" is :- All-cause mortality, encompassing death from any cause These is the endpoint used to evaluate the prognostic significance of NLR and PLR in hemodialysis patients.

Trial Locations

Locations (1)

Hemodialysis Unit; 🇪🇬 Sohag, سوهاج, Egypt