Vascular Occlusive Diseases Such as Diabetic Foot Treated With Mesenchymal Stem Cell

Chinese PLA General Hospital1 site in 1 country20 target enrollmentJanuary 2013

ConditionsDiabetic Foot Lower Limb Ischemia

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Diabetic Foot
Sponsor: Chinese PLA General Hospital
Enrollment: 20
Locations: 1
Primary Endpoint: Frequency of Adverse Events
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Mesenchymal stem cells with multidirectional differentiation potential,autologous stem cell transplantation into ischemic foot, make its differentiation to form new blood capillary, improve and restore the local blood flow.

Registry

clinicaltrials.gov

Start Date

January 2013

End Date

December 2017

Last Updated

11 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Chinese PLA General Hospital

Responsible Party

Principal Investigator

Xiaobing Fu

Academician

Chinese PLA General Hospital

Eligibility Criteria

Inclusion Criteria

•the age of 30-78 years old, men and women there is no limit.
•in accordance with the ministry of health in higher medical colleges and universities teaching material the sixth edition of the annals of diabetic foot diagnostic criteria.
•with severe lower limb ischemia (defined as the resting state of ankle brachial index (ABI) 0.4-0.85, accompanied by resting or intermittent toe line.
•treatment on a voluntary basis, and sign the informed consent.

Exclusion Criteria

•with severe heart, liver, kidney, lung function failure or general condition is very poor can't tolerate the stem cell transplant.
•clear over the past five years tumor markers in patients with malignant disease and blood levels increased significantly.
•the prodrome of acute infectious diseases.
•participated in clinical subjects within three months before test.
•adherence is poor, can not complete the course.