Exploratory Clinical Study on the Effectiveness of Glycyrrhizin in Early Vascular Lesions of Systemic Sclerosis

Sumida Hayakazu0 个研究点目标入组 20 人开始时间: 2019年3月18日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1)systemic sclerosis patients (Ministry of Health, Labor and Welfare Japan, diagnostic criteria 2016)
•2)Patients whose age ranges from 20 years to under 80 when acquiring consent
•3)After receiving sufficient explanation for the participation of this study, patients who obtained document consent by the patient's free will with sufficient understanding

•1)Patients with aldosteronism, myopathy or hypokalemia
•2)Patients with cirrhosis with more than 70 microgram/dL serum ammonia concentration
•3)Patients less than 3 months after the final administration of the other test drugs or investigational drugs
•4)Patients with more than 10 MRSS (modified Rodnan total skin thickness score)
•5)Patients with not satisfy% VC 80% and % DLCO 70% in respiratory function test
•6)Patients with eGFR less than 45 mL / min / 1.73 m2
•7)Patients with more than RVSP>40mmHg pulmonary hypertension
•8)Patients with complications of systemic lupus erythematosus or dermatomyositis
•9)Patients with a history of malignant tumors
•10)Patients with a history of severe hypersensitivity or anaphylactic reaction to the components of test drug
•11)patient judged by doctor as inappropriate

发起方

Sumida Hayakazu