Ringerâ??s lactate versus normal saline for children with severe dehydration due to acute diarrhea: A randomized double blind controlled trial

The Director0 个研究点目标入组 100 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•Children aged 1 month to 12 years diagnosed severe dehydration due to acute diarrhea as per WHO criteria: Acute diarrhea will be defined as more or equal 3 loose or watery or liquid or semiliquid stools in 24 hours. Severe dehydration will be defined as presence of hypotension i.e mean arterial blood pressure less than 5th percentile for age, sex and height or any of the two out of four signs - lethargic or unconscious, sunken eyeballs, drinks poorly or not able to drink, skin pinch goes back very slowly more than 2 seconds)

•1. Duration of diarrhea more than 7 days
•2. Bloody diarrhea
•3. Severe malnutrition as per WHO criteria (Symmetrical oedema, Weight-for-height: SD-score less than â??3 (less than70%) (Severe wasting)and or
•Height-for-age: SD-score less than â??3 (less than 85%) (Severe stunting).
•4. Known systemic disease (cardiac, endocrine, neurologic, chronic renal failure)
•5. Lethal malformations
•6. Children who have already received RL or NS during this episode.

发起方

The Director