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Single Session Pain Psychology Treatment: Comparative Efficacy & Mechanisms

Not Applicable
Completed
Conditions
Chronic Low Back Pain
Interventions
Behavioral: Health Education (HE)
Behavioral: "Empowered Relief" (ER)
Behavioral: Cognitive Behavioral Therapy (CBT)
Registration Number
NCT03167086
Lead Sponsor
Stanford University
Brief Summary

This study aims to compare the efficacy of a single session psychological treatment, "Empowered Relief" (ER), with the current standard of care, group Cognitive Behavioral Therapy (CBT) specifically on individuals with chronic low back pain who have pain-specific distress as indexed by pain catastrophizing scores.

Detailed Description

This is a randomized 3-arm study comprised of 2 active psychological treatments (ER \& CBT) and a health education (HE) arm that controls for time and attention. Study goals are to provide scientific evidence to demonstrate the efficacy of ER, and also provide a comparison of said efficacy against the current gold standard group treatment for PC -- manualized 8-session pain-CBT.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
263
Inclusion Criteria
  • Axial low back pain without radicular symptoms
  • Pain duration ≥ 6 months (per recent NIH Task Force on Research Standards for Chronic Low Back Pain based on participant self-report
  • Average pain intensity ≥4/10 for the past month at screening visit
  • English fluency
  • Males and females 18-70 years of age
  • Pain Catastrophizing Score (PCS) ≥20
Exclusion Criteria
  • Gross cognitive impairment
  • Active suicidal ideation or severe depression
  • Previous attendance in the active treatment groups (any ER classes ever taken or CBT in the past 3 years)
  • Participating in any interventional research study or completed participation in the last 2 months; enrollment in an observational study is acceptable
  • Current substance abuse
  • Clear likelihood to disrupt fellow class participants (e.g., personality disorder) at the discretion of the study team

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Health Education (HE)Health Education (HE)The active control treatment arm consists only of Health Education and has no psychological treatment components. It is a 2-hour HE class matched to the single-session psychological experimental arm (ER) on 4 important factors: duration, structure, format and site.
Single Session Skills-Based Pain Psychology Class"Empowered Relief" (ER)"Empowered Relief (ER)": A single-session skills-based approximately 2-hr group intervention for chronic pain.
Cognitive Behavioral Therapy (CBT)Cognitive Behavioral Therapy (CBT)8-week Manualized Pain-CBT Group Intervention will be delivered by PhD-level psychotherapists (3 in total).
Primary Outcome Measures
NameTimeMethod
Trait Pain Catastrophizing (Trait PC)3 months Post-Treatment

Change in Trait Pain Catastrophizing (Trait PC) from baseline to 3 months post-treatment across all treatment groups

Secondary Outcome Measures
NameTimeMethod
Trait PC at 6 months Post-treatment6 months Post-Treatment

Change in Trait Pain Catastrophizing (Trait PC) from baseline to 6 months post-treatment across all treatment groups

PROMIS Measures at 3 months Post-treatment3 months Post-Treatment

Change in score of PROMIS domains for chronic pain - including pain intensity, physical functioning, and emotional functioning - from baseline to post-treatment 3 months across all three treatment groups

Actigraphy for function and sleepSeveral time frames from baseline to 3 months Post-Treatment

Change in activity \& sleep measures from baseline to post-treatment across all treatment groups

Trial Locations

Locations (1)

Stanford University, Systems Neuroscience and Pain Lab

🇺🇸

Palo Alto, California, United States

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