The effect of vitamin D in the treatment of heart failure
Not Applicable
- Conditions
- Cardiac, heart or myocardial failure NOSheart failure.
- Registration Number
- IRCT2016102113678N13
- Lead Sponsor
- Vice Chancellor for research of Urmia University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
Inclusion criteria : class 3 of the New York Heart Association Classification(NYHA); ejection fraction less than 50% ; treated with heart failure medications in the last 3 months ; the level of vitamin D less than 20 ng/ml.
Exclusion criteria : vitamin D reception in the last 2 months ; acute gastrointestinal problems ;using interacting drugs with the homeostasis of vitamin D such as Corticosteroids , Thyroxine , anti-epileptic drugs, Tetracycline, Ketoconazole, Cholestyramine, Phenobarbital and Phenytoin ; bone fractures ; continuous consumption of cigarettes; kidney disease ; malignancies ; need to change the type and amount of drugs during the study
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method B type natriuretic peptide. Timepoint: before and after intervention. Method of measurement: ELISA.;High sensitivity C-reactive protein. Timepoint: before and after intervention. Method of measurement: ELISA.;Tumor necrosis factor alpha. Timepoint: before and after intervention. Method of measurement: ELISA.;Vitamin D. Timepoint: before and after intervention. Method of measurement: ELISA.;6 minute walk distance test. Timepoint: before and after intervention. Method of measurement: walking distance (meter).
- Secondary Outcome Measures
Name Time Method Systolic blood pressure. Timepoint: before and after intervention. Method of measurement: manometer.;Diastolic blood pressure. Timepoint: before and after intervention. Method of measurement: manometer.;Weight. Timepoint: before and after intervention. Method of measurement: scale.;Body mass index. Timepoint: before and after intervention. Method of measurement: with BMI formula.