Opium tincture and methadone syrup effectiveness for management of opium withdrawal
Phase 3
- Conditions
- opium Withdrawal.Mental and behavioural disorders due to psychoactive substance usewithdrawal state
- Registration Number
- IRCT2012122511885N1
- Lead Sponsor
- Vice chancellor for research, Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 74
Inclusion Criteria
Meeting the DSM-IV-TR criteria for opium dependence; first time detoxification; age range 18- 60 years .
Exclusion criteria: Physical illnesses that needed methadone consumption; using other substances (other opioids, cannabinoids, alcohol, benzodiazepines and etc); major psychiatric disorders such as bipolar mood disorder, major depression, severe anxiety disorders and psychotic disorders; major physical diseases such as hepatitis, tuberculosis, AIDS and etc; pregnancy; lactation.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Opium withdrawal sign & symptom. Timepoint: Daily (Within 10 days of drug administration). Method of measurement: Objective Opioid Withdrawal Scale (OOWS).
- Secondary Outcome Measures
Name Time Method Side effects of drugs. Timepoint: Daily (Within 10 days of drug administration). Method of measurement: Questionnaire.