NCT06468540尚未招募不适用
Comparative Study on the Efficacy of the Combination of Micropulse Laser With or Without Photodynamic Therapy in the Treatment of Chronic Central Serous Chorioretinal Disease
Beijing Hospital0 个研究点目标入组 60 人开始时间: 2024年6月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 主要终点
- BCVA
研究概览
简要总结
In this study, patients with chronic central serous chorioretinopathy who were treated by micropulse laser alone or micropulse laser combined with photodynamic therapy without drugs are retrospectively included. The visual acuity changes, subretinal fluid absorption and choroidal characteristics of the two groups are compared 1 to 6 months after treatment. We will also analyze baseline characteristics that influence post-treatment outcomes to identify potential predictors of poor treatment outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >18 years old.
- •The patient diagnosed with chronic central serous chorioretinopathy with a history of more than 6 months. The diagnostic criteria for chronic CSC were as follows: FFA examination showed leakage of strong fluorescent spots with the extension of angiography time, and late fluorescence accumulation, accompanied by decreased central vision, darkening of vision, and deformable microopia. Fundus examination showed superficial detachment of retinal neuroepithelium in macula.
- •Patients received single micropulse laser therapy or micropulse laser combined with drug-free photodynamic therapy, and had not received other laser or surgical treatment in the six months prior to treatment.
- •Patients had follow-up data before and after treatment for 1 month and at least 6 months.
排除标准
- •Patients with other fundus diseases or refractive interstitial opacity.
- •During treatment, other treatments other than micropulse laser or drug-free photodynamic therapy were received.
- •Various reasons led to incomplete patient data.
结局指标
主要结局
BCVA
时间窗: 1 month and 6 months
Best-corrected visual acuity using logMAR
CRT
时间窗: 1 month and 6 months
Central retinal thickness on OCT
次要结局
- SFCT(1 month and 6 months)
研究者
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