Assisted Hatching Versus Endometrial Scratch in Recurrent Implantation Failure.A Comparative Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 主要终点
- number of patients with positive pregnancy test
研究概览
简要总结
300 recurrent implantation failure patients will be alternatively assigned to assisted hatching , endometrial scratch , and no treatment ,100 patients in each group
详细描述
Group 1 consists of 100 patients will undergo endometrial scratch followed by controlled ovarian hyperstimulation Group 2 consists of 100 patients will undergo controlled ovarian hyperstimulation& assisted hatching Group 3 consists of 100 patients will undergo controlled ovarian hyperstimulation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •recurrent implantation failure
- •normal uterine cavity by transvaginal ultrasound
排除标准
- •endometrial polyp or fibroid distorting the endometrium
- •hydrosalpinx
- •preimplantation genetic diagnosis
- •severe male factor
研究组 & 干预措施
Endometrial scratch group
endometrial scratch controlled ovarian hyperstimulation
干预措施: endometrial scratch (Procedure)
Endometrial scratch group
endometrial scratch controlled ovarian hyperstimulation
干预措施: controlled ovarian hyperstimulation (Procedure)
Assisted hatching group
assisted hatching controlled ovarian hyperstimulation
干预措施: assisted hatching (Procedure)
Assisted hatching group
assisted hatching controlled ovarian hyperstimulation
干预措施: controlled ovarian hyperstimulation (Procedure)
ovarian stimulation only group
controlled ovarian hyperstimulation
干预措施: controlled ovarian hyperstimulation (Procedure)
结局指标
主要结局
number of patients with positive pregnancy test
时间窗: 2 months
次要结局
未报告次要终点
研究者
suzy abdelaziz Abdelhamid
lecturer of obstetrics & gynecology
Kasr El Aini Hospital