Evaluation with electrical impedance tomography (EIT) of the application of a High-Frequency Chest Wall Oscillation device to clear airway secretions

Not Applicable

Completed

• Conditions: Impaired cough with tracheobronchial secretion retention; Acute Respiratory Failure; High-Frequency Chest Wall Oscillation (HFCWO); Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12615001257550
• Lead Sponsor: Federico Longhini, MD

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

All the patients meeting the following criteria will be eligible for the study: 1) age equal or greater than 18 years; 2) presence of consciousness; 3) previous invasive mechanical ventilation > 48 hours.

Exclusion Criteria

Patients will be excluded if meeting one or more of the following criteria: 1) major cardiac arrhythmias or ischemia; 2) presence of pneumothorax or emphysema; 3) abdominal or esophageal or spinal surgery in the previous 72 hours; 4) acute spinal injuries; 5) presence of shock status; 6) cerebral hypertension; 7) presence of broncho-pleural fistula or pulmonary embolism; 8) chest trauma with rib cage injury; 9) recent (1 week) thoracic surgery; 10) presence of chest burns; 11) presence of hemoptysis; 12) pregnancy and 13) consent withdraw.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate if the application of a HFCWO device will different influence the lung aeration (as assessed by the end-expiratory lung impedence through EIT) in relation to: 1) the presence or absence of airway secretions and 2) the application of a RM.[At baseline and then immediately after (T0), after 1 (T1) and 3 (T3) hours the application of the HFCWO]

Secondary Outcome Measures

Name	Time	Method
To evaluate if the application of a HFCWO device will different influence the tidal volume (as assessed by the tidal impedence variation through EIT) in relation to: 1) the presence or absence of airway secretions and 2) the application of a RM.[At baseline and immediately after (T0), after 1 (T1) and 3 (T3) hours the application of the HFCWO];To evaluate if the application of a HFCWO device will different influence the gas exchange (as assessed with arterial blood gases) in relation to: 1) the presence or absence of airway secretions and 2) the application of a RM.[At baseline and immediately after (T0), after 1 (T1) and 3 (T3) hours the application of the HFCWO];To evaluate if the application of a HFCWO device will different influence vital parameters (i.e. heart rate and blood pressure) in relation to: 1) the presence or absence of airway secretions and 2) the application of a RM.[At baseline and immediately after (T0), after 1 (T1) and 3 (T3) hours the application of the HFCWO]