Comparison of Dexmedetomidine, Ketamine and Magnesium Sulphate for treatment of Perioperative Shivering after Spinal Anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 1
研究概览
简要总结
This study is a prospective double blind randomized clinical trial to compare dexmedetomidine ketamine and magnesium sulphate for the treatment of perioperative shivering following spinal anesthesia. Adult patients aged 18 to 60 years who develop grade 2 or 3 shivering after spinal anesthesia will be randomly allocated into three groups. Each group will receive a single intravenous bolus of either dexmedetomidine 0.5 microgram per kg ketamine 0.5 mg per kg or magnesium sulphate 50 mg per kg at the onset of shivering.
The time taken for reduction of shivering to grade 0 or 1 will be recorded. Patients will be monitored for heart rate mean arterial pressure oxygen saturation temperature and sedation score at regular intervals. Recurrence of shivering and adverse effects such as nausea vomiting hypotension bradycardia respiratory depression delirium and hypothermia will also be recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of age 18 to 60 years of ASA grade 1, 2 and 3 undergoing elective surgery under spinal anaesthesia with grade 2 and above shivering.
排除标准
- •Patients with ASA physical status above
- •Patients allergic or contraindicated to study medication.
- •Patients with severe cardio pulmonary disease, renal or liver impairment, peri operative fever or hypothermia, history of seizure, massive blood transfusion and history of psychiatric illness.
研究者
Devam Himanshu Trivedi
JSS Academy Of Higher Education And Reasearch