A Comparative study of Adjunct Dexmedetomidine and Magnesium sulphate on Hemodynamic response during Laproscopic Surgery under General Anaesthesia: An Academic Trial.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- Compared to magnesium sulphate, dexmedetomidine demonstrates superior efficacy in stabilizing hemodynamic parameters during pneumoperitoneum in laparoscopic procedures under general anaesthesia.
研究概览
简要总结
Aim of this study is to identify the relative efficacy of Dexmedetomidine and Magnesium Sulfate on attenuation of hemodynamic responses in laparoscopic Surgery under General Anaesthesia.
This study isa Double blinded Randomised controlled rial study to be conducted in the Department of Anaesthesiology at Asansol District Hospital over a period of 12 months. 102 patients were randomly allotted in 2 groups of 18-60 years, with ASA physical groups I and II posted for laparoscopic surgery under General Anaesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Double
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients schedule for elective laparoscopic surgery.
- •ASA I and II.
排除标准
- •Patient refusal, Patients undergo emergency surgery.
结局指标
主要结局
Compared to magnesium sulphate, dexmedetomidine demonstrates superior efficacy in stabilizing hemodynamic parameters during pneumoperitoneum in laparoscopic procedures under general anaesthesia.
时间窗: Baseline – Before administration of study drug (after IV line placement, before induction). | After loading dose – 10 minutes after drug administration, before induction. | At intubation. | 5 minutes after intubation. | At creation of pneumoperitoneum. | Every 15 minutes intraoperatively. | At extubation. | Postoperatively at 5,15, minutes in PACU (Post Anaesthesia Care Unit)
次要结局
- Less Heart rate, Blood pressure & Mean arterial pressure variability with dexmedetomidine during critical intraoperative periods.(Baseline – Before administration of study drug (after IV line placement, before induction).)
研究者
Dr Ritika Ranjan
Asansol District Hospital