Dietary Effects on Weight Loss and Lipid Profile in Sedentary Women

Not Applicable

Completed

• Conditions: Obesity; Life Style; Overweight
• Interventions: Dietary Supplement: LCD; Dietary Supplement: NCD

• Registration Number: NCT03066882
• Lead Sponsor: P.L.Shupik National Medical Academy of Post-Graduate Education

Brief Summary

Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method. The present study aimed to determine the effects of negative-calorie diet on weight loss and lipid profile, and to compare its efficiency with low-calorie diet.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05-10
• Primary Completion: 2015-09-20
• Study Completion: 2016-10-30
• Status Verified: 2017-02
• Study First Submitted: 2017-02-17
• Study First Submitted QC: 2017-02-23
• Last Update Submitted: 2017-02-23
• Study First Posted: 2017-03-01
• Last Update Posted: 2017-03-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 37

Inclusion Criteria

• Non-smokers and weight-stable (± 2 kg, for more than one year) with no history of regular exercise in at least three months before the study.

Exclusion Criteria

• History of CVD and other disorders such as diabetes, depression, eating disorders, chronic medications, kidney disease, cancer, food allergies or intolerances to items used in meals.
• Subjects with abnormality in thyroid or Electrocardiograph, any history of anti-obesity medication or weight loss drugs or dietary supplementations for weight control.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Study group II	LCD	Study group II (18 participants) received the LCD or healthy weight maintenance diet (details of diet: 15% protein, 55% carbohydrates, 30% fat).Both groups had 15% caloric restriction from their maintenance energy requirements.
Study group I	NCD	Study group I (19 participants) received the NCD (details of diet: 15% protein, 75% carbohydrates, 10% fat). Both groups had 15% caloric restriction from their maintenance energy requirements.

Primary Outcome Measures

Name	Time	Method
Weight	pre-study	assessed in kg
Total cholesterol (Total-C)	pre-study	assessed in mg/dl
High-density lipoprotein -cholesterol (HDL-C)	pre-study	assessed in mg/dl
Low-density lipoprotein -cholesterol (LDL-C)	pre-study	assessed in mg/dl
Triglycerides (TG)	pre-study	assessed in mg/dl

Secondary Outcome Measures

Name	Time	Method
Total cholesterol (Total-C)	3-month	assessed in mg/dl
Weight	3-month	assessed in kg
High-density lipoprotein -cholesterol (HDL-C)	3-month	assessed in mg/dl
Low-density lipoprotein -cholesterol (LDL-C)	3-month	assessed in mg/dl