Dietary Effects on Weight Loss and Lipid Profile in Sedentary Men

Not Applicable

Completed

• Conditions: Life Style; Overweight; Men; Lipid Metabolism Disorders; Obesity
• Interventions: Dietary Supplement: LCD; Dietary Supplement: NCD

• Registration Number: NCT03082794
• Lead Sponsor: P.L.Shupik National Medical Academy of Post-Graduate Education

Brief Summary

Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method. The present study aimed to determine the effects of negative-calorie diet on weight loss and lipid profile, and to compare its efficiency with low-calorie diet in men.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-02-20
• Primary Completion: 2012-09-20
• Study Completion: 2012-12-27
• Status Verified: 2017-03
• Study First Submitted: 2017-03-04
• Study First Submitted QC: 2017-03-12
• Study First Posted: 2017-03-17
• Last Update Submitted: 2017-03-17
• Last Update Posted: 2017-03-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 104

Inclusion Criteria

• Non-smokers
• Weight-stable (± 2 kg, for more than one year)
• No history of regular exercise (in at least three months before the study).

Exclusion Criteria

• History of medical disorders (CVD and other such as diabetes, depression, eating disorders, chronic medications, kidney disease, cancer, food allergies or intolerances to items used in meals, abnormality in thyroid or Electrocardiograph
• History of anti-obesity medication or weight loss drugs or dietary supplementations for weight control.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Study group II	LCD	Study group II (51 participants) received the LCD or healthy weight maintenance diet (details of diet: 15% protein, 55% carbohydrates, 30% fat).Both groups had 15% caloric restriction from their maintenance energy requirements.
Study group I	NCD	Study group I (53 participants) received the NCD (details of diet: 15% protein, 75% carbohydrates, 10% fat). Both groups had 15% caloric restriction from their maintenance energy requirements.

Primary Outcome Measures

Name	Time	Method
Low-density lipoprotein -cholesterol (LDL-C)	Baseline	assessed in mg/dl
Triglycerides (TG)	Baseline	assessed in mg/dl
Total cholesterol (Total-C)	Baseline	assessed in mg/dl
High-density lipoprotein -cholesterol (HDL-C)	Baseline	assessed in mg/dl
Weight	Baseline	assessed in kg

Secondary Outcome Measures

Name	Time	Method
Total cholesterol (Total-C)	3-month	assessed in mg/dl
High-density lipoprotein -cholesterol (HDL-C)	3-month	assessed in mg/dl
Low-density lipoprotein -cholesterol (LDL-C)	3-month	assessed in mg/dl
Weight	3-month	assessed in kg