Effect of weight loss on improvement of liver inflammation and fibrosis in non- alcoholic fatty liver patients through calorie restricted diet
Not Applicable
- Conditions
- on-Alcoholic Fatty Liver - Non -Alcoholic Steatohepatitis.Other specified inflammatory liver diseases
- Registration Number
- IRCT2017081535707N1
- Lead Sponsor
- Vice Chancellor for research of Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1. BMI 25-40? Hepatic fibrosis 2 and higher? Liver enzymes 1.5 times more natural
Exclusion criteria: Viral hepatitis B, c ? Liver Cancer? alcohol consumption? Pregnancy ? Hepatic autoimmune diseases? Taking hepatotoxic drugs? Taking vitamin D supplement pills ? Patient's denial? Failure to observe the diet
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cytokeratin 18. Timepoint: First, 3 and 6 months after intervention. Method of measurement: ELIZA Kit.;Liver dysfunction factors. Timepoint: First.3 and 6 months after intervention. Method of measurement: Biochemistry Lab.
- Secondary Outcome Measures
Name Time Method iver Fibrosis. Timepoint: First,6 months after intervention. Method of measurement: Fibroscan Of liver.;Anthropometric measurements. Timepoint: first, 3 and 6 months after the intervention. Method of measurement: BIA device. Measuring body size with meter.