A prospective study of the effects of weight loss on knee pain, function and appearance on x-ray in severely obese women.

Not Applicable

Completed

• Conditions: Knee pain; Diet and Nutrition - Obesity; Musculoskeletal - Osteoarthritis

• Registration Number: ACTRN12605000171617
• Lead Sponsor: Centre for Obesity Research and Education (CORE) Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-08-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

Body mass index greater than 35kg/m2, with a problem or symptom related to at least one knee joint and can give informed consent to participation in the study.

Exclusion Criteria

History of a known non-degenerative arthritic condition such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosis or gout, pregnancy, previous history of knee arthroplasty.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in knee symptoms[At 2 years]

Secondary Outcome Measures

Name	Time	Method
Radiological changes in knees. Elucidation of factors that predict a greater prevalence of knee symptoms, dysfunction and degenerative arthritis in severely obese women presenting for Lap-Band surgery, assessment of any relationship with degree of weight loss and change in knee symptoms.[At 2-years.]