Does weight loss associated with bariatric surgery improve sperm function?

Not Applicable

• Conditions: Obesity; metabolic syndrome; infertility; Reproductive Health and Childbirth - Fertility including in vitro fertilisation; Metabolic and Endocrine - Other metabolic disorders

• Registration Number: ACTRN12617000323325
• Lead Sponsor: Robinson Research Institute, University of Adelaide

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-03-01
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Male
• Target Recruitment: 216

Inclusion Criteria

Inclusion Criteria
(1) BMI >30 kg/m2 and a waist circumferences of >102cm. These are the current standard criteria for categorising obesity. A number of studies assessing male obesity and fertility have used waist circumference in conjunction with BMI, as waist circumference in humans has been determined to be a better indicator for cardio metabolic disease risk.
(2) Males aged 18-40years. ROS the primary outcome is not altered in this age range. There are also little reported changes to other sperm parameters to be measured in this age range.
(3) At recruitment, patient is on a participating clinic’s waiting list to undergo a first-time SG, ABG or RYGB. To ensure participants in the study are not having a revision or conversion which may confound results.

Exclusion Criteria

Exclusion Criteria (known con-founders)
(1) Males who have had vasectomies or vasectomy reversals.
(2) Males with un-descendent testes, suspected pathologies related to fertility (i.e. varicoceles) or known genetic disorders that effect weight and fertility (i.e. Klinefelter's Syndrome, Prader-Willi or Larence-Moon-Bardet-Biedel).
(3) Males diagnosed with azoospermia at initial assessment. During the study period any results with implications for future or current fertility or for general wellbeing will be noted, and results will be sent to participant’s general practitioners, with the option for participants to be referred to fertility specialists.

Study & Design

• Study Type: Observational
• Study Design: Not specified