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Cloxacillin as Prevention of Double Lumen Infection in Hemodialysis Patients

Not Applicable
Completed
Conditions
Double Lumen Infection
Hemodialysis
Interventions
Registration Number
NCT00885300
Lead Sponsor
Shiraz University of Medical Sciences
Brief Summary

The purpose of this study is to investigate whether cloxacillin lock is effective in prevention of double lumen infection.

Detailed Description

Double lumen infection is one of the causes of morbidity and mortality in hemodialysis patients. Many strategies used to prevent it and one of them is antibiotic lock. Thus we select chronic hemodialysis patients and divided them into 2 groups. One group received cloxacillin and heparin as catheter lock and the second group received only heparin lock.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
100
Inclusion Criteria
  • hemodialysis for 3 months
  • at least 2 time dialysis/week
Exclusion Criteria
  • active infection
  • acute renal failure

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1cloxacillincloxacillin 100 mg/ml + heparin 1000iu/ml as catheter lock at the end of hemodialysis
1heparincloxacillin 100 mg/ml + heparin 1000iu/ml as catheter lock at the end of hemodialysis
2heparinheparin 1000iu/ml as catheter lock at the end of hemodialysis
Primary Outcome Measures
NameTimeMethod
catheter infection6 months
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Shiraz University Hemodialysis Center

🇮🇷

Shiraz, Fars, Iran, Islamic Republic of

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