MedPath

Cloxacillin

Generic Name
Cloxacillin
Drug Type
Small Molecule
Chemical Formula
C19H18ClN3O5S
CAS Number
61-72-3
Unique Ingredient Identifier
O6X5QGC2VB
Background

A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.

Indication

Cloxacillin is indicated for the treatment of beta-hemolytic streptococcal, pneumococcal, and staphylococcal infections (including beta-lactamase producing organisms).

Associated Conditions
Infection caused by staphylococci, Infections caused by penicillinase-producing staphylococci, Pneumococcal Infection, Streptococcal Infections
Clinical Trials
Related News

Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia

Phase 4
Recruiting
Conditions
Staphylococcus Aureus Bacteraemia
Staphylococcal Bacteraemia
Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)
Staphylococcus (S.) Aureus Infection
Interventions
Drug: Penicillin G_1200mg
First Posted Date
2024-12-10
Last Posted Date
2025-03-12
Lead Sponsor
Region Skane
Target Recruit Count
420
Registration Number
NCT06726395
Locations
🇸🇪

Skånes universitetssjukhus, Region Skåne, Lund, Sweden

Non-inferiority Trial Comparing Cloxacillin vs Cefazolin in Methicillin-susceptible Staphylococcus Aureus Bacteremia

Not Applicable
Active, not recruiting
Conditions
Bacteremia Due to Methicillin Susceptible Staphylococcus Aureus
Interventions
First Posted Date
2017-08-14
Last Posted Date
2023-12-15
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
315
Registration Number
NCT03248063
Locations
🇫🇷

François-Xavier Lescure, Paris, France

Efficacy of a Short-term Sequential Therapy in Non-complicated Catheter Related Bacteremia by Methicillin- Susceptible S.Aureus.

Phase 3
Terminated
Conditions
Staphylococcus
Interventions
Drug: Cloxacilin
First Posted Date
2013-06-11
Last Posted Date
2015-08-07
Lead Sponsor
Fundación Pública Andaluza Progreso y Salud
Target Recruit Count
1
Registration Number
NCT01875263
Locations
🇪🇸

Hospital Universitario Reina Sofía, Córdoba, Spain

🇪🇸

Hospital de Antequera, Málaga, Spain

🇪🇸

Hospital Universitario Virgen de la Victoria, Málaga, Spain

and more 8 locations

Staphylococcus Aureus Bacteremia Antibiotic Treatment Options

Phase 3
Completed
Conditions
Staphylococcus Aureus Infection
Interventions
Drug: Trimethoprim-Sulfamethoxazole
First Posted Date
2013-02-15
Last Posted Date
2020-05-27
Lead Sponsor
Heinrich-Heine University, Duesseldorf
Target Recruit Count
215
Registration Number
NCT01792804
Locations
🇳🇱

Amsterdam, Amsterdam, Netherlands

🇳🇱

Tilburg, Tilburg, Netherlands

🇳🇱

Diakonessenhuis Utrecht, Utrecht, Netherlands

and more 37 locations

Cloxacillin as Prevention of Double Lumen Infection in Hemodialysis Patients

Not Applicable
Completed
Conditions
Double Lumen Infection
Hemodialysis
Interventions
First Posted Date
2009-04-21
Last Posted Date
2009-04-21
Lead Sponsor
Shiraz University of Medical Sciences
Target Recruit Count
100
Registration Number
NCT00885300
Locations
🇮🇷

Shiraz University Hemodialysis Center, Shiraz, Fars, Iran, Islamic Republic of

Once-Daily Amikacin Plus Cloxacillin in Febrile Neutropenic Children

Not Applicable
Completed
Conditions
Neutropenia
Fever
Cancer
First Posted Date
2005-08-12
Last Posted Date
2005-09-23
Lead Sponsor
Khon Kaen University
Target Recruit Count
166
Registration Number
NCT00129688

Telavancin for Treatment of Uncomplicated Staphylococcus Aureus Bacteremia

Phase 2
Completed
Conditions
Gram-Positive Bacterial Infections
Interventions
First Posted Date
2003-06-12
Last Posted Date
2019-01-16
Lead Sponsor
Cumberland Pharmaceuticals
Target Recruit Count
60
Registration Number
NCT00062647
Locations
🇺🇸

Wellstar Infectious Disease, Marietta, Georgia, United States

© Copyright 2025. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy