Role of intraoperative and postoperative fluid restriction on postoperative outcomes after esophagectomy â?? a prospective randomized controlled trial
Phase 3
- Conditions
- Health Condition 1: null- intraoperative and postoperative fluid restriction on postoperative outcomes after esophagectomy
- Registration Number
- CTRI/2013/03/003496
- Lead Sponsor
- Tata Memorial Hospital Dr Ernest Borges Marg Parel Mumbai
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other (Terminated)
- Sex
- Not specified
- Target Recruitment
- 324
Inclusion Criteria
1.Patients with biopsy or cytology proven (squamous or adenocarcinoma) esophageal cancer
2.Patients with staging investigations indicating operability
3.Surgical plan for total transthoracic or transhiatal esophagectomy
4.American Society of Anesthesiologists (ASA) grade I, II
Exclusion Criteria
1.Patients with low performance status (ECOG score > 1)
2.Patients with pre existing renal or liver disease
3.Patients with ischemic heart disease
4.Patients below 18 years and above 70 years of age.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pulmonary complications in the two groupsTimepoint: Pulmonary complications in the two groups
- Secondary Outcome Measures
Name Time Method 1.Need for postoperative ventilation <br/ ><br>2.Duration of postoperative ventilation <br/ ><br>3.Need for tracheostomy for pulmonary toilet <br/ ><br>4.Need for frequent bronchoscopies (5) <br/ ><br>Timepoint: 1.Need for postoperative ventilation <br/ ><br>2.Duration of postoperative ventilation <br/ ><br>3.Need for tracheostomy for pulmonary toilet <br/ ><br>4.Need for frequent bronchoscopies (5) <br/ ><br>