Fluid Balance and Clinical Outcomes

Completed

• Conditions: Fluid Balance; Input and Output; Inflammatory Mediators; Acute Kidney Injury; Mortality

• Registration Number: NCT01168583
• Lead Sponsor: University of Florida

Brief Summary

This study is about investigating the relationship of postoperative fluid balance, inflammation and acute kidney injury. This is a non-interventional study (no drug administration). The investigators will collect baseline demographic data, postoperative fluid balance status by Intake-output data, follow routine labs and collect 1 blood sample (0.5ml) with morning lab draws on day 1 and 5ml urine samples on day 1 and 2.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07
• Study First Submitted: 2010-07-22
• Study First Submitted QC: 2010-07-22
• Study First Posted: 2010-07-23
• Primary Completion: 2011-06
• Study Completion: 2011-06
• Status Verified: 2011-09
• Last Update Submitted: 2011-09-19
• Last Update Posted: 2011-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Age 18 years or older, and
• Undergoing elective cardiothoracic surgery(s), alone or in combination with other procedures/surgery(s): thoracic aortic aneurysm, cardiac valves, coronary artery bypass grafting, abdominal thoracic aneurysm, and other cardiovascular surgery.

Exclusion Criteria

• Pregnancy
• History of any organ transplant
• Preoperative intra-aortic balloon pump (IABP)
• Current use of natriuretic peptides
• ESRD patients on dialysis
• Estimated GFR < 30ml/min using MDRD equation.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Shands Hospital, University of Florida; 🇺🇸 Gainesville, Florida, United States