Genicular nerve bipolar radiofrequency ablation for chronic osteoarthritis knee pain: A double-blind randomized controlled trial
- Conditions
- Chronic knee osteoarthritis pain and response for treatment (Genicular nerve bipolar radiofrequency ablation VS dexamethasone injection)Chronic knee osteoarthritis pain, genicular nerve, radiofrequency ablation, genicular bipolar radiofrequency, knee pain, knee arthritis
- Registration Number
- TCTR20170130003
- Lead Sponsor
- /A
- Brief Summary
We found that a substantial proportion of individuals experienced meaningful pain relief with RFA or sham RFA coupled with local anesthetic and steroid injections, with no statistically significant or clinically important differences between groups. In conjunction with recent evidence suggesting that ablating 3 nerves may not be sufficient to treat knee OA and that targeting more than 3 nerves provides better outcomes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 64
1.Age 18 - 85 years and persistent knee pain > 6 months
2.Diagnosis of radiologically verified Kellgren-Lawrence grade III or IV osteoarthritis
3.No response to conservative treatment
4.Positive response to diagnostic geniculate nerve block
1.Acute knee pain with inflammation
2.Taking anticoagulant
3.History of knee surgery
4.Serious psychiatric/neurological problems
5.Known radiculopathy
6.Intraarticular injection during previous 3 months : steroids, hyaluronic acid
7.Previous RF treatment
8.Connective tissue disease affecting knee
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain Score Preintervention, Postintervention 1st, 2nd, 4th, 6th, 8th, 10th, 12th month Numerical Rating Scale (NRS)
- Secondary Outcome Measures
Name Time Method Knee function and Patient Satisfaction Preintervention, Postintervention 1st, 2nd, 4th, 6th, 8th, 10th, 12th month Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and patient global impression,Procedural Complication Preintervention, Postintervention 1st, 2nd, 4th, 6th, 8th, 10th, 12th month Descriptive Data