The effect of pomegranate juice concentrate in women with polycystic ovary syndrome
- Conditions
- Polycystic Ovary Syndrome.
- Registration Number
- IRCT20191109045383N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 44
18=Age=40
BMI = 25
Being single
Not having acute and chronic diseases such as: cardiovascular disease, kidney, liver, diabetes, hypothyroidism, hyperthyroidism, asthma, neoplastic, hyperprolactinemia, malabsorption disorders, hypertension, dyslipidemia, (new or during 6 months).
No Depression
Not following a specific diet.
Not following a specific exercise program.
Non-use of drugs such as contraceptive pills (Oral contraceptive pill), hormonal drugs, anti-diabetic drugs, anti-obesity drugs, antioxidant supplements and multivitamin minerals, blood lipid lowering drugs.
Not smoking
Not allergic to pomegranate and its products.
Not consuming pomegranates and pomegranate-containing products at least 2 months before starting the study
Pregnancy
Not consuming Concentrated Pomegranate Juice completely
Not willing to continue participating in the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of malondialdehyde in women with polycystic ovary syndrome. Timepoint: Baseline and 8 weeks after starting the study. Method of measurement: Measurement of serum malondialdehyde by calorimetric method using kiazist kit.
- Secondary Outcome Measures
Name Time Method Evaluation of total antioxidant capacity in women with polycystic ovary syndrome. Timepoint: Baseline and 8 weeks after starting the study. Method of measurement: Measurement of serum total antioxidant capacity by cupric reducing antioxidant capacity (CUPRAC) method using kiazist kit.;Evaluation of insulin resistance in women with polycystic ovary syndrome. Timepoint: Baseline and 8 weeks after starting the study. Method of measurement: Measurement of Insulin Resistance Using Formula (fasting plasma glucose (mMol/L) × insulin (µIU/mL))/22.5. The levels of serum insulin will be determined using ELISA kit (AccuBind, Monobind Inc., USA) and fasting blood sugar will be measured by enzymatic photometric method using standard kits (Pars Azmun, Tehran, Iran).;Depression score. Timepoint: Baseline and 8 weeks after starting the study. Method of measurement: Depression Anxiety Stress Scale-21 (DASS-21) questionnaire.