Optic Nerve Sheath Diameter in Prediction of Fluid Responsiveness

• Conditions: Shock; Fluid Responsiveness; Optic Nerve Sheath Diameter
• Interventions: Device: Optic Nerve Sheath Diameter (ONSD) measurement by ultrasound

• Registration Number: NCT04092036
• Lead Sponsor: Tanta University

Brief Summary

The aim of the study to examine Optic Nerve Sheath Diameter measurement for prediction of fluid responsiveness in hemodynamically unstable patients

Detailed Description

Not available

Study Timeline

• Status Verified: 2019-09
• Study First Submitted: 2019-09-13
• Study First Submitted QC: 2019-09-14
• Last Update Submitted: 2019-09-14
• Study First Posted: 2019-09-17
• Last Update Posted: 2019-09-17
• Study Start: 2019-10-15
• Primary Completion: 2020-03-14
• Study Completion: 2020-03-14

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Patients on mechanical ventilation
• 18 years or older
• patients developing hypotension (Mean arterial blood pressure) <65 mmHg

Exclusion Criteria

• Patients with Spontaneously breathing activity.
• Patients with a history of intracranial disease e.g. (stroke, TBI, causes of increased intracranial pressure).
• local cause in the eye as (Glaucoma, Single eye)
• Need for high PEEP.
• Known history of cardiac disease.
• Organ/s failure at admission

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Unstable patients	Optic Nerve Sheath Diameter (ONSD) measurement by ultrasound	Patients on mechanical ventilation, 18 years or older and developing hypotension (Mean arterial blood pressure) \<65 mmHg

Primary Outcome Measures

Name	Time	Method
The cut-off value of optic nerve sheath diameter (ONSD) for prediction of fluid responsiveness	first day

Secondary Outcome Measures

Name	Time	Method
Correlation between Stroke Volume Variation (by electrical cardiometry) and ONSD	first day