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临床试验/CTRI/2025/05/086426
CTRI/2025/05/086426尚未招募不适用

Comparison of Postoperative Pain in Single-Rooted Teeth With Asymptomatic Apical Periodontitis Using Two Bioceramic Sealers and Two Different Root Canal Tapers: A Single-Blind Randomized Controlled Trial

Dr Poornima Wazarkar1 个研究点 分布在 1 个国家目标入组 112 人开始时间: 2025年5月20日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
112
试验地点
1
主要终点
Post operative pain scores

研究概览

简要总结

Postoperative pain is the most common occurrence after endodontic treatment. It occurs mainly due to mechanical, chemical or microbial injury to periapical tissues. Root canal sealers plays a crucial role in this regard by coming in contact with periapical tissues through apical foramen and lateral canals causing a localised inflammation with direct influence on degree of post-operative pain based on composition of sealers. In this regard, bioceramic sealers offer a major advantage of biocompatibility and ability to form a hermetic seal. Furthermore, bioceramic sealers enhance endodontic treatment outcomes by differentiation of odontoblasts and release of bioactive substances which aid in periapical healing. Many authors have reported apical preparations to sizes larger than recommended to completely disinfect the root canal. On the contrary, it is often argued that larger preparation size results in unnecessary removal of dentin leading to weakening of tooth structure. Recently, new injectable Bioceramic sealers have been developed possessing better properties like uniform consistency and flow which allow them to penetrate into irregularities and accessory canals of root canal system, ultimately improving the quality of obturation and endodontic outcome. No literature was found which compared the effect of root canal tapers on postoperative pain using BioActive RCS root canal sealer which is relatively new Bioceramic sealer. Hence this study is designed.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Cooperative healthy patients who are willing to participate in the study and sign consent form.
  • Age: 18-60 years Teeth: single rooted teeth with asymptomatic apical periodontitis indicated for RCT.
  • Radiographic changes limited to slight widening of PDL space and loss of lamina dura.

排除标准

  • Pregnant, medically compromised and patients with uncontrolled diabetes are excluded from the study.
  • Patient unable to give informed consent.
  • Patient taken any medication like analgesic, antibiotics, 24 hours before treatment visit.

结局指标

主要结局

Post operative pain scores

时间窗: Post operative pain scores at 6 hours, 12 hours, 24 hours, 48 hours and 72 hours between the group A and group B

次要结局

  • Post operative pain scores(Post operative pain scores at 6 hours, 12 hours, 24 hours, 48 hours & 72 hours between subgroups A1, A2, B1 & B2)

研究者

发起方
Dr Poornima Wazarkar
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Poornima Wazarkar

Bharati Vidyapeeth Dental College and Hospital, Navi Mumbai

研究点 (1)

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