NCT05213325Unknown不适用
Evaluation of Serum Interleukin 6 and 8 in Children With Acute Gastroentritis
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Serum level of Interleukin 6
研究概览
简要总结
Cytokines, such as IL-6 and IL-8 can be used as markers of acute infections, including acute gastroenteritis. This study aims to evaluate serum levels of interleukins 6 and 8 in children with acute gastroenteritis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 6 Months 至 5 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children aged 6 months to 5 years.
- •Acute diarrhea: defined according to WHO criteria as the "passage of loose or watery stools at least three times in a 24 h period", lasts less than 14 days, with or without fever or vomiting, but considering the importance of change in stool consistency rather than frequency, and the usefulness of parental insight in deciding whether children have diarrhea or not.
排除标准
- •Malnutrition or obesity
- •History of antibiotic therapy in the last 72 hours.
- •Acute diarrhea in association with systemic infections
- •Malignancy
- •Chronic diarrhea
- •Autoimmune and autoinflammatory diseases.
- •Chronic renal/liver failure
- •Diabetes mellitus
- •Group 2: Controls (Healthy control children)
- •Inclusion Criteria:
- •Healthy children aged 6 months to 5 years.
- •Exclusion Criteria:
- •Acute diarrhea
- •Malnutrition or obesity
- •History of antibiotic therapy in the last 72 hours.
- •Acute diarrhea in association with systemic infections
- •Malignancy
- •Chronic diarrhea
- •Autoimmune and autoinflammatory diseases.
- •Chronic renal/liver failure
- •Diabetes mellitus
结局指标
主要结局
Serum level of Interleukin 6
时间窗: Within the first 3 days of acute diarrhea
Difference in serum level of interleukin 6 between cases and control groups
Serum level of Interleukin 8
时间窗: Within the first 3 days of acute diarrhea
Difference in serum level of interleukin 8 between cases and control groups
次要结局
未报告次要终点
研究者
John Samuel Shaker
resident doctor at pediateric department sohag university hospital
Sohag University
研究点 (1)
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