Cytokine Assay for Early Identification of Pediatric Stem Cell Transplant Recipients

Terminated

• Conditions: Blood Stem Cell Transplant Failure

• Registration Number: NCT01135355
• Lead Sponsor: Stanford University

Brief Summary

The aim of our study is to determine whether a clinically relevant laboratory measurement (of seven specific immunologic biochemicals in the blood) can identify which bone marrow transplant recipients are likely to progress to respiratory failure. Our ultimate goal is to devise a comprehensive and inclusive laboratory test that is effective at determining who is likely to go on to respiratory failure, in order to facilitate early medical intervention.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2008-07
• Study First Submitted: 2010-06-01
• Study First Submitted QC: 2010-06-01
• Study First Posted: 2010-06-02
• Primary Completion: 2010-12
• Study Completion: 2011-01
• Status Verified: 2024-06
• Last Update Submitted: 2024-06-18
• Last Update Posted: 2024-06-21

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

• Hematopoietic stem cell transplantation (HSCT) for any indication.

• Patients will range from age 0 to age 21. There is no gender restriction. We expect the male to female ratio to end up being about 50/50
• Ability to understand and the willingness to sign a written informed consent document.

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Compute median flourescence intensity, standard curves, and estimated pg/mL for each cytokine.	weekly during hospitalization for transplant

Trial Locations

Locations (1)

Stanford University School of Medicine; 🇺🇸 Stanford, California, United States