Feasibility of a Cytokine Expression Profile in Immune Cells as an Orientation Tool in Therapeutic Decisions for Auto-inflammatory and Auto-immune Diseases
Not Applicable
Completed
- Conditions
- Rheumatoid Arthritis
- Registration Number
- NCT03280797
- Lead Sponsor
- Centre Hospitalier Universitaire de Nīmes
- Brief Summary
This study will assess the feasibility of using cytokine expression profiles in blood samples as a method for evaluating rheumatoid polyarthritis
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
- The patient must have given their free and informed consent and signed the consent form
- The patient must be a member or beneficiary of a health insurance plan
- Patient is at least 18 years old
- Subjects included as patients have rheumatoid polyarthritis according to ACR EULA 2010, DAS28>3.2 criteria
- Subjects included as controls are healthy volunteers who have no overexpression of cytokines
Exclusion Criteria
- The subject is participating in an interventional study, or is in a period of exclusion determined by a previous study
- The subject refuses to sign the consent
- It is impossible to give the subject informed information
- The patient has had at least 3 months of specific treatment that can potentially impact cytokine profile
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Dosage of cytokines between groups Day 0 Concentration measured by ELISA and flow cytometry
- Secondary Outcome Measures
Name Time Method Creation of biobank Day 0 Storage of blood samples
Trial Locations
- Locations (2)
CHU de Montpellier
🇫🇷Montpellier, France
CHU Nimes
🇫🇷Nîmes, France
CHU de Montpellier🇫🇷Montpellier, France