Home blood pressure monitoring versus standard care in hypertension for stroke/TIA survivors – TASMIN5S/BPTogether

Not Applicable

Completed

• Conditions: Blood pressure monitoring in people who have had a stroke or transient ischaemic attack (TIA); Circulatory System; Stroke, not specified as haemorrhage or infarction

• Registration Number: ISRCTN57946500
• Lead Sponsor: niversity of Oxford

Brief Summary

2023 Interim results article in https://pubmed.ncbi.nlm.nih.gov/36639797/ Feasibility results (added 16/01/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-09-06
• Study Completion: 2021-01-31
• Last Update Posted: 30 January 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 610

Inclusion Criteria

1. Participant is willing and able to give informed consent for participation in the study
2. Male or female, aged 18 years or above
3. Previous history of stroke and/or specialist confirmed TIA at least one month before randomisation
4. Baseline systolic blood pressure > 130mmHg (mean of 2nd and 3rd readings)
5. Willing and able to comply with all study procedures

Exclusion Criteria

1. Diagnosis of dementia (Clinical Code)
2. Score over 10 on the short orientation memory concentration test
3. Any other significant disease or disorder which, in the opinion of the Investigator, may put the participants at risk because of participation in the trial
4. Pregnancy
5. BP > 180/110mmHg at baseline (to be referred to GP but could be subsequently rescreened if < 180/110mmHg)
6. More than three antihypertensives
7. Unwilling to self-monitor
8. Receiving care for blood pressure by a specialist rather than a primary care physician
9. Stage 4 CKD or worse – i.e.: eGFR less than 30 mL/min/1.73 m2 (as these persons are more likely to be managed by specialists, are more prone to Acute Kidney Injury and/or hyperkalemia and less responsive to certain antihypertensives?)
10. Diagnosed atrial fibrillation
11. Orthostatic hypotension: more than 20mmHg systolic drop after standing for 1 minute. Not relevant if participant unable to stand
12. Participation in other studies that concern hypertension and/or adjustment of antihypertensive medication

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Difference in systolic blood pressure (SBP) at 1 year comparing intervention and control groups, using the mean of the 2nd and 3rd readings and adjusted for baseline systolic blood pressure and other covariates