Predicting Factors of Post-Total Thyroidectomy Hypocaӏcemia

Completed

• Conditions: Hypocalcemia After Total Thyroidectomy

• Registration Number: NCT07211581
• Lead Sponsor: Al Safwa University College

Brief Summary

Predicting post-total thyroidectomy hypocalcemia involves a combination of patient-specific, disease-related, and surgical factors. Key predictive factors include the intrinsic characteristics of the thyroid disease, pre-operative levels of calcium and vitamin D, the degree of parathyroid gland manipulation or injury, advanced age, and pre-existing hyperthyroidism. While no single factor is definitive, a low post-operative parathyroid hormone (iPTH) level is a strong indicator of developing hypocalcemia

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-09
• Study Start: 2025-09-17
• Primary Completion: 2025-09-17
• Study Completion: 2025-09-17
• Study First Submitted: 2025-09-17
• Study First Submitted QC: 2025-09-30
• Last Update Submitted: 2025-09-30
• Study First Posted: 2025-10-08
• Last Update Posted: 2025-10-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 123

Inclusion Criteria

1. patients requiring total thyroidectomy.
2. age between 18-75 years old
3. both gender
4. no co-existing disease.

Exclusion Criteria

1. previous hemithyroidectomy, lobectomy, resection of the parathyroid gland. 2. 2. patients with missing laboratory data, previous subtotal thyroidectomy.

3. diagnosed pathology of the parathyroid gland

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
hypocalcemia incidence	1 day and 2 weeks after surgery
hypocalcemia other factors related to clinical status.	1 day and 2 weeks after surgery	Comparison of Serum Calcium levels of the studied group reported Comparison of PTH levels between hypocaӏcemia and Eucalcemic

Trial Locations

Locations (1)

Mustaqbal University; 🇹🇳 Sfax, Safx, Tunisia