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Clinical Trials/NCT00766389
NCT00766389
Unknown
Not Applicable

Retinal Nerve Fiber Layer Thickness Analysis With Cirrus HD OCT Versus Stratus OCT

Yonsei University1 site in 1 country200 target enrollmentOctober 2008
ConditionsGlaucoma

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Glaucoma
Sponsor
Yonsei University
Enrollment
200
Locations
1
Primary Endpoint
Retinal nerve fiber layer thickness
Last Updated
17 years ago

Overview

Brief Summary

The Cirrus HD OCT, a new spectral domain optical coherence tomography (OCT), has better resolution than the previous time domain Stratus OCT. Discriminating ability of these two OCTs for diagnosis of glaucoma and judgement of disease progression will be studied.

Detailed Description

The Cirrus HD OCT is a new spectral domain OCT. Even though its resolution and speed are much better than the previous time domain Stratus OCT, its diagnostic power for glaucoma detection and judgement of disease progression should be directly compared with Stratus OCT. In the present study, we will review the data of peripapillary retinal nerve fiber layer thickness measurement using the Cirrus HD OCT and Stratus OCT. Their discriminating ability for diagnosis of glaucoma and judgement of disease progression will be compared using the ROC curves and Cohen's kappa.

Registry
clinicaltrials.gov
Start Date
October 2008
End Date
February 2009
Last Updated
17 years ago
Study Type
Observational
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Retinal nerve fiber layer analysis with Cirrus OCT and Stratus OCT within 1 month

Exclusion Criteria

  • Intraocular surgeries history
  • High refractive error ( \< -4.00 diopters, or \> + 4.00 diopters)
  • Media opacity

Outcomes

Primary Outcomes

Retinal nerve fiber layer thickness

Time Frame: When the OCT images are taking

Secondary Outcomes

  • Visual field(When the OCT images are taking)
  • Red-free fundus photo(When the OCT images are taking)
  • Intraocular pressure(When the OCT images are taking)
  • Central corneal thickness(When the OCT images are taking)

Study Sites (1)

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