Neutrophil to Lymphocyte ratio and Platelet to Lymphocyte ratio as a Prognostic indicator for Post Operative laparotomy patients in Intensive care unit- A observational study

Not yet recruiting

Conditions: Complications of gastric band procedure,

Registration Number: CTRI/2024/09/073243

Lead Sponsor: All India Institute of Medical Sciences

Brief Summary: **Study Title:**â€œNeutrophil to Lymphocyte ratio and Platelet to Lymphocyte ratio as a Prognostic indicator for Post Operative laparotomy patients in Intensive care unit- A Prospective observational studyâ€

**Study Objectives:**

**Primary:** To assess role of NLR and PLR for predicting the ICU   Stay in post-operative laparotomy patient.

**Secondary:**1. To compare predictability of NLR and PLR with other prognostic indicators like               CRP, lactate, Procalcitonin. 2. To assess the cost benefit ratio.

**Study Design**- Prospective Observational Study

**Study Setting**- All post operative laparotomy patient admitted in ICU, All India Institute of Medical Science, Bhubaneswar.

**Study Groups** - All patient age more than 18years operated under General Surgery Department Who are admitted to ICU after surgery for at-least 24hrs.

**Sample size**- 150

**Novelty:** No studies have been so far published from India which predicts the course of post operative laparotomy   ICU patient based on NLR and PLR.

**Participant Recruitment: will start after approval**

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 150

Inclusion Criteria

1.All patient age more than 18years who are taken up for Laparotomy under Department of General Surgery and subsequently admitted in ICU for at- least 24hrs After Surgery.

Exclusion Criteria

1.Pregnancy 2.Immunodeficiency disorder 3.Hematological disorder 4.Operated vitally stable patient otherwise normal in postoperative period if chosen for ICU Treatment after 24hrs.
5.Failed to understand or sign the informed consent will be excluded.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Survivor, Non survivor measurement	till stay in ICU

Secondary Outcome Measures

Name	Time	Method
Predictability of the NLR & PLR in defining the ICU course.	Baseline-At admission

Trial Locations

Locations (1): AIIMS Bhubaneswar
🇮🇳
Khordha, ORISSA, India
AIIMS Bhubaneswar
🇮🇳Khordha, ORISSA, India
Dr S Manwar Ali
Principal investigator
9488820340
alysmanwar@yahoo.co.in