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Community Pharmacists and Opioid Misuse

Not Applicable
Completed
Conditions
Opioid Misuse
Interventions
Behavioral: Standard Medication Counseling (SMC)
Behavioral: Brief Intervention Medication Therapy Management
Registration Number
NCT03149718
Lead Sponsor
University of Utah
Brief Summary

Opioid medication misuse and overdose have reached epidemic proportions in the US. Community pharmacy is a potentially valuable resource for addressing opioid medication misuse. This study will manualize and establish the feasibility, acceptability, and clinical effect of a community pharmacist-led intervention aimed at: improving opioid mediation regimen adherence, eliminating misuse, connecting patients to additional care, and safeguarding against overdose.

Detailed Description

The current small scale single-blinded randomized controlled study will build on our preliminary studies by manualizing and examining the feasibility, acceptability, and clinical effect for the Brief Intervention Medication Therapy Management (BI-MTM) model. BI-MTM is a multicomponent community pharmacy-based intervention. BI-MTM is designed to: (1) promote opioid medication regimen adherence, (2) reduce opioid medication misuse, (3) connect participants with patient navigation (a chronic condition care model) to increase self-management of health conditions that increase risk for misuse, and (4) provide naloxone rescue training referrals. Patients will be screened across 14 months for opioid medication misuse in an urban community pharmacy affiliated with a major medical system. Patients positive for misuse will be randomly assigned to BI-MTM (n=23) or Standard Medication Counseling (n=23). Standard Medication Counseling is the Centers for Medicaid and Medicare Services requirement for pharmacists in the US wherein pharmacy patients filling prescriptions receive information and opt-in counseling. This study will demonstrate feasibility and acceptability of BI-MTM for community pharmacy patients who misuse their opioid medications for future intervention implementation in a fully powered randomized trial. This study will also generate preliminary data regarding opioid medication misuse elimination and increases in participant self-management activation for comorbid health conditions that increase risk for misuse.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
46
Inclusion Criteria
  • Opioid Misuse

    -≥18 years

  • English speaking

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Exclusion Criteria
  • Are pregnant (given potential pre/post-natal opioid use complications among pregnant women/offspring)
  • Cannot provide collateral contact information for ≥2 contact persons (to ensure consistent contact/follow up)
  • Do not have a reliable landline or mobile phone to be contacted by study staff
  • Are only filling buprenorphine (given some formulations are not indicated for pain)
  • Plan to leave the area for an extended period of time in the next 3 months
  • Have had a psychotic and/or manic episode in the last 30 days
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
SMC (n=23)Standard Medication Counseling (SMC)Standard Medication Counseling.
BI-MTM (n=23)Brief Intervention Medication Therapy ManagementBrief Intervention Medication Therapy Management.
Primary Outcome Measures
NameTimeMethod
Intervention feasibilityMonth 21 of Study

Intervention feasibility will be established through delivery of all BI-MTM components to 85% of BI-MTM recipients.

Intervention acceptabilityMonth 21 of Study

Intervention acceptability will be demonstrated though qualitative interviews.

Secondary Outcome Measures
NameTimeMethod
Opioid MisuseMonth 21 of Study

Opioid misuse will be demonstrated by the Prescription Opioid Misuse Index (POMI).

Patient Self-ManagementMonth 21 of Study

Patient self-management activation misuse than will be captured by the Patient Activation Measure.

Trial Locations

Locations (2)

Falk Pharmacy

🇺🇸

Pittsburgh, Pennsylvania, United States

Medicine Shoppe

🇺🇸

Somerset, Pennsylvania, United States

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