A comparison of efficacy of oral prednisolone plus tacrolimus and azathioprine in the treatment of pemphigus vulgaris
Phase 2
- Conditions
- pemphigus vulgaris.Pemphigus vulgaris
- Registration Number
- IRCT2012073010450N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
46 patients from 20 to 80 years old; new pemphigus vulgaris or new disease activity; the clinical diagnosis of pemphigus vulgaris will be based on clinical presentation and histological analysis (+/- immunofluorescences study) of at least 1 biopsy specimen from the skin or the mucosa. Exclusion criteria: Having contraindications for the use of azathioprine, tacrolimus or prednisolone; any history of hypersensitivity to these drugs; active infection; pregnancy; lactation or no ability to attend follow-up; severe side effect during the study period.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method