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Effect of early mobilisation combined with additional protein on muscle mass in critically ill patients

Conditions
Decline in muscle mass during ICU admission.
Registration Number
NL-OMON20948
Lead Sponsor
Medisch Spectrum Twente
Brief Summary

one

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

Included and randomized in the study within 48 hours after ICU admission.

- Expected to stay on the ICU for at least 72 hours.

Exclusion Criteria

-Complete parenteral feeding -> administration of ProSource not possible

-Chronic renal failure or hepatic encephalopathy -> absolute contraindications of supplemental protein

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Muscle thickness of the mid-upper arm, forearm and thigh measured by ultrasonography
Secondary Outcome Measures
NameTimeMethod
•muscle quality (echogenicity determined with ultrasonography);<br /><br>•nutritional state and hydration status (Biva measurement);<br /><br>•muscle force (MRC-sum and handgrip force);<br /><br>•functional status (DEMMI);<br /><br>•quality of life (EQ-5D);<br>
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