Comparison of the efficacy of IV paracetamol and IV ketoprofen in the treatment of renal colic in emergency department : a two-center double blind randomized study.

Phase 1

• Conditions: Comparison of the efficacy of IV paracetamol and IV ketoprofen in the treatment of renal colic; Therapeutic area: Diseases [C] - Symptoms and general pathology [C23]

• Registration Number: EUCTR2015-002381-23-FR
• Lead Sponsor: CHU de Nîmes

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09-11
• Last Update Posted: 3 April 2017

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• informed consent
• The patient is available for telephone follow-up to one week
• The patient is at least 18 years old.
• suspected renal colic
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 338
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 338

Exclusion Criteria

• The patient has contreindication for a necessary treatment in this study.
• The patient has an allergy to ketoprofen or paracetamol , of gastric or intestinal ulcer , bleeding disorders, a history of asthma triggered by taking ketoprofen or similar activity substances
• The patient has hyperthermia, hemodynamic instability, oligoanuria .
• The patient has an initial pain assessed by NRS 10/10 .
• The patient has a history of aneurysm or aortic dissection, kidney transplant , single kidney, liver or kidney failure .
• ketoprofen or paracetamol administration four hours before treatment to emergencies.aracétamol 4 heures avant le traitement en structure d'urgence.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified