Comparison of different drug combinations with respect to changes in pulse rate and blood pressure during induction of anaesthesia.
Phase 3
Completed
- Conditions
- Health Condition 1: null- Patients undergoing elective procedures under general anaesthesia requiring endotracheal intubation.
- Registration Number
- CTRI/2018/05/014307
- Lead Sponsor
- Malvika Gupta
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
ASA Physical status 1 and 2 patients
Exclusion Criteria
Known history of hypersensitivity to etomidate, propofol or ketamine, egg or soya; BMI >30 kg/sq.m; History of postural hypotension, diabetes mellitus, cardiovascular diseases; GERD; Pregnancy; Anticipated difficult airway
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie Etomidate's haemodynamic effects during anaesthesia induction in CTRI/2018/05/014307?
How do Propofol-Ketamine and Propofol-Etomidate combinations compare to standard anaesthetic regimens in managing intubation-induced hypertension?
What biomarkers correlate with reduced sympathetic response to laryngoscopy in the CTRI/2018/05/014307 trial drug combinations?
What adverse events are associated with Etomidate-based anaesthesia in phase III trials for endotracheal intubation?
How do Propofol-Etomidate interactions influence GABAergic and corticosteroid receptor pathways during anaesthesia induction?