Clinical and Radiographic Assessment Of Immediate Implant With Topical Vitamin D and Xenograft Mixture: A Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- clinically: A)Loss of crestal bone. B)Stability of implant. Radiographically: crestal bone loss by periapical radiograph in millimeters.
研究概览
简要总结
What is the difference between grafting the jumping gap upon using xenograft mixed with topical vitamin D clinically regarding crestal bone level and implant stability, radiographically regarding crestal bone level after implant insertion in the posterior region of mandible?
详细描述
Effect of Vitamin D on Bone Regeneration .Vitamin D is known for its role in the skeletal system. Vit D deficiency is also widely researched for its effects on the healing of fractures, bone defects and osseointegration of implants. There are studies that investigated the effects of dietary supplementation with vitamin D to reduce vitamin D deficiency but increasing the serum level of this vitamin takes time therefore, an attempt has been made to combat the effect of vitamin D deficiency through topical application. up to the knowledge, upon search of literatures, there is not enough studies that correlate topical application of vitamin D with xenograft mixture as filling space material. this study is to Assess immediate implant with topical vitamin D and xenograft mixture clinically and Radiographically.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The American Society of Anesthesiologist (ASA) I , II
- •Both Genders. 3- Patients having unrestorable tooth on the posterior mandibular region
- •The patient who have complete their facial growth and teeth eruption
- •No bone disease or lesion in propose implant site
排除标准
- •Poor oral hygiene patients and/or patients
- •Patients with active acute infection.
- •Patients with bad oral habits.
- •Pregnant or lactating women.
- •Heavy smokers.
- •Alcohol and drug addicts.
- •Diabetes disease
研究组 & 干预措施
vit D mixed with xenograft
Topical application of vitamin D solution mixed with xenograft in the jumping gap around immediate implant
干预措施: vit D mixed with xenograft (Drug)
only xenograft without vit D
grafting the jumping gap with xenograft only around immediate implant
干预措施: only xenograft without vit D (Drug)
结局指标
主要结局
clinically: A)Loss of crestal bone. B)Stability of implant. Radiographically: crestal bone loss by periapical radiograph in millimeters.
时间窗: clinically: Loss of crestal bone by periodontal prop assessed in millimeters in six months Stability of implant by OSTTEL assessed as ISQ values in six months crestal bone loss in millimeters will be one ,three months and six months.
the loss of crestal bone after implant insertion using periodontal probe in millimeters. implant stability using OSTELL device. Postoperative follow up using periapical radiographs to evaluate crestal bone loss in millimeters will be after, one ,three months and six months by standardized parallel periapical digital technique radiograph .The radiographs will be done by using: The Kavo Scan eXamTM One and the Rinn extension cone paralleling (XCP)periapical film holder will be used to achieve standardization of digital radiographs.
次要结局
未报告次要终点
研究者
Mohamed elsaeed
master candidate oral and maxillofacial surgery
Suez Canal University