adding dexmedetomidine and neostigmine and midazolam to bupivacaine 0.25% in management postoperative pain by caudal anesthesia

Phase 3

• Conditions: Hypospadias; Undescended and ectopic testicle; Condition 1: Diverticular disease. Condition 2: lower abdominal surgeries. Condition 3: appendicitis. Condition 4: Inguinal hernias. Condition 5: hypospadias. Condition 6: Undescended testicle. Condition 7: Intussusception. Condition 8: Volvulus. Condition 9: intestinal obstruction. Condition 10: caudal anesthesia.; Diverticular disease of intestine; Acute appendicitis; Inguinal hernia; Intussusception; Volvulus; Other impaction of intestine; K56.1

• Registration Number: IRCT20230124057200N1
• Lead Sponsor: Arak University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

All children 2-8 years old (patients) candidates for lower abdominal surgery referring to Valiasr Hospital
ASA Class I, II patients
Patients whose surgery duration is between 45-90 minutes

Exclusion Criteria

All patients with underlying diseases of the heart, lungs, liver, etc.
History of seizures
Allergy to the drugs used in the study
Patients in whom the caudal block cannot be performed

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain level. Timepoint: during recovery after surgery and 1, 2, 4, 6, 12 and 24 hours after surgery. Method of measurement: CHEOPS Criteria.

Secondary Outcome Measures

Name	Time	Method
Average analgesic consumption. Timepoint: Within 24 hours after surgery. Method of measurement: patient file.;Mean arterial blood pressure. Timepoint: Every 15 minutes during surgery. Method of measurement: Mercury sphygmomanometer.;Pulse rate. Timepoint: Every 15 minutes during surgery. Method of measurement: pulse oximeter.