Repeated MRI to correlate rectal tumour motion to rectal wall motion: a feasibility study in order to develop a dose escalation strategy for rectal cancer

Completed

• Conditions: colorectal carcinoma; rectal cancer; 10017990; 10017991

• Registration Number: NL-OMON32591
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Rectal tumour < 15cm from the anal verge
Receiving 5x5 Gy short course pre-operative radiotherapy
Written informed consent

Exclusion Criteria

Patients who meet exclusion criteria for MRI following the protocol of the department of radiology UMC Utrecht
Patients with history of pelvic surgery
Patients with other pelvic malignancies
Patients with inflammable bowel diseases or diverticulitis

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Quantification of rectal tumour motion and correlation with rectal wall<br /><br>movements using one (cine-)MRI in order to develop a CBCT controlled dose<br /><br>escalation strategy for rectal cancer. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>