MedPath

Comparison of Bupivacaine and Exparel for Carpal Tunnel Release

Not Applicable
Withdrawn
Conditions
Pain After Carpal Tunnel Release
Interventions
Registration Number
NCT02141178
Lead Sponsor
University of Pittsburgh
Brief Summary

Carpal tunnel syndrome is one of the most common surgeries performed per year in the United States, accounting for over 600,000 surgeries. The procedure is commonly performed under light sedation and local anesthesia. Bupivicaine, a long acting local anesthetic, has been used to allow extended pain relief for 8-10 hours after carpal tunnel release. Exparel, a liposomal bupivicaine formulation, has been documented to provide pain relief for up to 72 hours post-operatively. By decreasing post-operative pain through the use of a long-acting local anesthetic, the use of narcotic pain medications may be decreased and patient satisfaction scores may increase.

The purpose of this study is to prospectively compare bupivicaine and liposomal bupivicaine with respect to post-operative pain control, narcotic usage, and patient satisfaction after carpal tunnel release.

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Patients with carpal tunnel syndrome undergoing surgery
Exclusion Criteria
  • Non english speaking
  • Allergy to bupivacaine or exparel

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
ExparelExparelPatients will received Exparel subcutaneously for local anesthesia during surgery
BupivacaineBupivacainePatients will received 0.5% Bupivacaine subcutaneously for local anesthesia during surgery
Primary Outcome Measures
NameTimeMethod
PainStarting immediately after surgery and then every 8 hours for 10 days

Pain will be evaluated using an 11-point ordinal scale (0-10)

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University of Pittsburgh Medical Center

🇺🇸

Pittsburgh, Pennsylvania, United States

© Copyright 2025. All Rights Reserved by MedPath