ow-dose gamma knife radiosurgery plus whole-brain radiation therapy for multiple brain metastases: a multi-institutional prospective study
Phase 2
- Conditions
- Metastatic brain tumors
- Registration Number
- JPRN-UMIN000027361
- Lead Sponsor
- Fujieda Heisei Memorial Hospital
- Brief Summary
After GK plus WBRT for 40 patients, 31 did not develop further intracranial recurrence until death or last follow-up, whereas 9 developed recurrence. With a follow-up period up to 24 months, the overall survival rate was 36% at 12 months and median survival time was 8 months. The cumulative incidence of intracranial recurrence was 25% at 12 months.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
(1)Active double cancer (2)In pregnancy or lactation period (3)Psychiatric disorder (4)Allergy to gadolinium contrast or contraindication of MR imaging
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method