MedPath

Smellprints in lung Cancer; the role of ENose in diagnosis and Treatment (SCENT) part 5: Diagnostic value of the eNose in Colorectal Cancer

Completed
Conditions
bowel cancer
colorectal carcinoma
10017990
Registration Number
NL-OMON34063
Lead Sponsor
Medisch Centrum Leeuwarden
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

Written informed consent obtained.
Colorectal cancer:
• adult 18-80 years
• histological proven CRC
Controls:
Matched for:
• Age: <50 yr, 50>=age=<70, 70• smoking status: two groups
A. never, or ex-smoker > 3 months
B. current smoker or ex-smoker < 3 months.
• sex
• Normal findings at colonoscopy performed for various reasons like e.g. irritable bowel syndrome and familial adenomatous polyposis.

Exclusion Criteria

• periodontitis
• any infection (especially of the airways) in the last 4 weeks
• known pulmonary disease
• Other or former malignancy
• Diabetes mellitus (documented in the past)
• Pregnancy
• Untreated hypercholesterolaemia (documented in the past)
• Significant cardiovascular disease (documented in the past)
• Healthy controls: Any abnormal findings at colonoscopy (e.g. like polyps)

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>primary outcome parameter is the difference in breathprints provided by the<br /><br>electronic nose </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>not applicable</p><br>
© Copyright 2025. All Rights Reserved by MedPath