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Effect of the BTL-899 Therapy for Non-invasive Lipolysis and Circumference Reduction of Abdomen

Not Applicable
Completed
Conditions
Improvement of Abdomen Appearance
Interventions
Device: BTL-899
Registration Number
NCT03270150
Lead Sponsor
BTL Industries Ltd.
Brief Summary

The study is a prospective open-label single-arm study that includes three treatment procedures and four follow-up visits.

Detailed Description

This study will evaluate the clinical efficacy and safety of the BTL-899 device for non-invasive lipolysis and circumference reduction of abdomen. The study is a prospective open-label single-arm study. The subjects will be enrolled and assigned into a single study group. Subjects will complete three (3) treatment visits and will be invited to four (4) follow-up visits 1, 2, 3 and 6-months after the final treatment. 6-months follow-up visit is the optional one.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Age ≥ 21 years
  • Voluntarily signed informed consent form
  • BMI ≤ 35 kg/m2
  • Women of child-bearing potential are required to use birth control measures during the whole duration of the study
  • Subjects willing and able to abstain from partaking in any treatments other than the study procedure to promote body contouring during study participation
  • Subjects willing and able to maintain his/her regular (pre-procedure) diet and exercise regimen without effecting significant change in either direction during study participation
Exclusion Criteria
  • Cardiac pacemakers
  • Cardiovascular diseases
  • Implanted defibrillators, implanted neurostimulators
  • Electronic implants
  • Disturbance of temperature or pain perception
  • Pulmonary insufficiency
  • Metal implants
  • Drug pumps
  • Malignant tumor
  • Hemorrhagic conditions
  • Septic conditions and empyema
  • Acute inflammations
  • Systemic or local infection such as osteomyelitis and tuberculosis
  • Contageous skin disease
  • Elevated body temperature
  • Pregnancy
  • Breastfeeding
  • Injured or otherwise impaired muscles
  • Scars, open lesions and wounds at the treatment area
  • Basedow's disease
  • Previous liposuction in the treatment area in the last six months
  • Abdominal wall diastasis
  • Unstable weight within the last 6 months
  • Previous body contouring treatments in the abdomen area in the last three months

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
BTL-899 Therapy ArmBTL-899BTL-899 therapy, 3 therapies
Primary Outcome Measures
NameTimeMethod
Efficacy of the BTL-899 treatment for abdomen circumference reduction after the final follow-up visit4 months

Evaluation of change in abdomen circumference using tape measurements in cm at the final follow-up visit.

Occurrence of adverse events7 months

The occurrence of adverse events will be followed throughout the whole study.

Secondary Outcome Measures
NameTimeMethod
Efficacy of the BTL-899 treatment for abdomen circumference reduction4 months

Evaluation of change in abdomen circumference using tape measurements in cm at all study visits after the first therapy.

Therapy comfort during the study treatment.1 month

Therapy comfort during the treatment evaluated through the Therapy Comfort Questionnaire (10-point scale).

Efficacy of BTL-899 treatment for fat and circumference reduction in abdomen, as assessed by two blinded evaluators4 months

Evaluation of photographs before and after the treatment.

Subject's satisfaction with study treatment4 months

Subject's satisfaction with the therapy results evaluated through the Subject Satisfaction Questionnaire (5-point scale).

Ultrasound imaging4 months

Evaluation of ultrasound images.

Trial Locations

Locations (1)

Aesthe Clinic

🇧🇬

Sofia, Bulgaria

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