NL-OMON36442
Completed
Not Applicable
Coronary Artery Plaque Characterisation with Non-invasive Multi-Slice Computed Tomography and Invasive Intravascular Ultrasound and Optical Coherence Tomography in Patients with Acute Coronary Syndromes Without ST-segment Elevation - Non-invasive and invasive plaque characterisation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- atherosclerosis
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 50
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Chest pain suggestive for myocardial ischemia for at least 30 minutes;
- •\- Electrocardiogram (ECG) with ST\-segment shifts (ST\-segment depression \>1 mm in at least two contiguous leads or transient ST\-segment elevation \> 1mm with duration of \< 30 min in at least two contiguous leads) and/or T\-wave changes (T\-wave inversion \> 1\.5 mm in at least three contiguous leads);
- •\- Positive hs Troponin T \> 14 ng/L or positive Troponin T \<0\.01 µg/L
- •\- Clinical indication for invasive coronary angiography followed by PCI of the ischemia\-related target lesion;
- •\- Informed consent.
Exclusion Criteria
- •\- Persistent ST\-elevation of \>1 mm in 2 or more leads;
- •\- Need for emergency invasive coronary angiography and PCI;
- •\- Need for emergency coronary artery bypass grafting;
- •\- Presence of cardiogenic shock;
- •\- Estimated glomerular filtration rate (eGFR) \< 50 ml/min;
- •\- Known allergy to iodine contrast agents;
- •\- Cardiac rhythms other than sinus rhythm;
- •\- Inability to lay supine;
- •\- Inability tot sustain a breath\-hold for 15 seconds;
- •\- Inability to provide informed consent.
Outcomes
Primary Outcomes
Not specified
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